The Acromegalic Imposter: a common missed diagnosis

The Acromegalic Imposter: a common missed diagnosis

There has been a lot of buzz online about a human diabetes paper suggesting diabetes may be more complex than historically thought. A paper in The Lancet: Diabetes and Endocrinology early this year suggests there may be as many as 5 types of diabetes in humans; instead of 2. This reminded me of a paper I had read in PLoS One regarding feline diabetes induced by hypersomatotropism.

Virus vector mediated gene therapy for the treatment of X-linked myotubular myopathy in dogs

Virus vector mediated gene therapy for the treatment of X-linked myotubular myopathy in dogs

A paper published earlier this year in Molecular Therapy detailed a successful dose dependent response of a usually fatal monogenic disorder of skeletal muscle in dogs to gene therapy. The disorder treated was X-Linked Myotubular Myopathy (XLMTM) which results from MTM1 gene mutations and deficiency in the protein that this gene encodes (myotubularin).